eSupervisor Detail

About me

I am a human geneticist with over five years of research experience in meiotic recombination and chromosome 21 nondisjunction. I completed my Ph.D. in Human Genetics from the University of Calcutta in 2023. My expertise spans molecular genetics, NGS analysis, and statistical genomics. As a guest lecturer, I teach genetics, biotechnology, molecular biology, and microbial genetics, integrating research experience with concept-driven, student-focused mentorship.

Interests: My area of research is Human Genetics, with a focused emphasis on the molecular mechanisms underlying meiotic recombination errors that lead to chromosome 21 nondisjunction and Down syndrome birth. My doctoral work explored maternal polymorphisms in key recombination regulator genes such as MCM9, RNF212, PRDM9, and SPO11, and their cumulative influence on recombination frequency, chiasma positioning, and age-related risk of nondisjunction. My research integrates molecular genetics, cytogenetics, statistical genomics, and in-silico functional analysis to understand how genetic variation disrupts genome stability during oogenesis. My research interests extend to the broader regulation of genome integrity, including the genetic and molecular determinants of chromosome segregation errors, gene–environment interactions, and translational implications for reproductive genetics. I am particularly interested in expanding my work into epigenetics, especially the role of epigenetic modifications in regulating recombination, chromatin architecture, and maternal age-associated genomic instability. I aim to investigate how epigenetic regulation and genome stress responses influence meiotic fidelity, thereby bridging classical genetics with emerging insights into chromatin dynamics and epigenomic control mechanisms.