Poonam Rani

Researcher

Research Data Analysis

Karnataka, India

6 Years

Joined May 2026

Indian Institute Of Science

Department Of Inorganic And Physical Chemistry

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About me

PhD research scholar at the Indian Institute of Science (IISc), Bangalore, with expertise in chemical biology, medicinal chemistry, and neurodegenerative disease research. Experienced in designing and developing small-molecule therapeutics, cell-based assays, fluorescence imaging, and in vivo disease models. Passionate about interdisciplinary research, scientific mentoring, and helping students understand the practical applications of chemistry in healthcare and drug discovery.

Interests: My research interests focus on neurodegenerative diseases, chemical biology, medicinal chemistry, and proteostasis. I am particularly interested in developing small-molecule modulators targeting the 20S proteasome for therapeutic intervention in disorders such as Alzheimer’s disease. I also work on fluorescence-based probes, cell biology assays, and in vivo model systems to study disease mechanisms and evaluate therapeutic efficacy.

Skills

Chemical BiologyMedicinal ChemistryDrug DiscoveryFACSConfocal MicroscopyCell culture and handlingin vitro and in vivo drug analysisDrosophila melanogasterwestern blottingprotein extractionSDS-PAGEMolecular dockingmolecular simulationBiochemical and enzymatic assayproject management and documentationliterature review and scientific data interpretation• Confocal imaging for cellular localization and fluorescence analysisimmunofluorescenceHandling Drosophila melanogaster flies, in vivo behavioral, olfactory conditioning, and pharmacological studies, tissue dissectionAutodock, PyMol, Gaussian, Discovery Studio Visualizer, Chem Draw, ADMET prediction tools, pharmacophore modeling

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