
Project Research Scientist Ii
Kusum Jain
Experiment Design
About me
I am a PhD researcher in Zoology with specialization in Medical Mycology, with research experience in antifungal resistance, fungal genomics, molecular epidemiology, fungal pathogenesis, and clinical and environmental surveillance of emerging fungal pathogens. My research primarily focuses on Candida auris and non-albicans Candida species, with particular emphasis on understanding the molecular mechanisms of antifungal resistance, genetic diversity, population structure, virulence-associated traits, and environmental adaptation of clinically important fungal pathogens. My expertise includes fungal identification and characterization, antifungal susceptibility testing (AFST), molecular biology, whole-genome sequencing (WGS), transcriptomics/RNA-seq, differential gene expression analysis, RT-qPCR, phylogenetics, population genomics, MLST, mutation analysis, sterol profiling, biofilm-associated studies, and genotype–phenotype correlation.
Interests: My research interests focus on the molecular epidemiology, antifungal resistance mechanisms, and pathogenesis of emerging fungal pathogens, particularly non-albicans Candida species. My work investigates the genetic and molecular basis of azole resistance, including mutations in resistance-associated genes, gene expression dynamics, copy number variations, and genomic adaptations. I am also interested in understanding the environmental persistence, transmission dynamics, and population structure of clinically important yeasts such as Candida auris, Candida tropicalis, Candida krusei, Lodderomyces elongisporus, and Wickerhamomyces anomalus. Additionally, my research explores novel antifungal agents and combination therapies to combat drug-resistant fungal infections, integrating genomic, transcriptomic, metabolomic, and immunological approaches to improve diagnosis, treatment, and infection control strategies.
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