eSupervisor Detail

About me

Ph.D. in Biochemistry with over 15 years of combined academic, research, and industry experience in molecular cardiology, translational biochemistry, and experimental life-science techniques. Founder and Director of Affyclone Laboratories Pvt. Ltd., with proven expertise in industry– academia collaboration, curriculum development, and delivery of value-added, skill-oriented courses for undergraduate and postgraduate students.

Interests: My research interests center on understanding the molecular mechanisms underlying cardiovascular diseases, particularly atherosclerosis, with emphasis on cell signaling pathways, lipid metabolism, and vascular inflammation that regulate plaque development and stability. I am particularly interested in exploring how bioactive phytochemicals and natural compounds modulate intracellular signaling pathways involved in oxidative stress, inflammation, and endothelial dysfunction. During my postdoctoral research at CSIR–Central Leather Research Institute (CLRI), Chennai, I investigated the regulation of the Hippo signaling pathway in cholesterol-induced atherosclerosis models, focusing on the role of lipid-mediated cellular signaling in vascular pathology. My doctoral research at the University of Madras examined the molecular mechanisms of oligomeric proanthocyanidins in regulating atherosclerotic plaque instability, specifically through the integrin–Src–FAK and PI3K/Akt/mTOR signaling pathways. Currently, at Affyclone Laboratories Pvt. Ltd. (Chennai), a biotechnology startup working in molecular biology reagents and biotechnology research applications , my research activities focus on experimental design, molecular biology techniques, and translational biotechnology applications. My work involves developing and optimizing molecular biology assays, biochemical analysis methods, and diagnostic reagent validation, with applications in cancer biology, cardiovascular research, and infectious disease studies. In addition to research activities, I actively guide undergraduate (UG), postgraduate (PG), and research scholars in designing and executing experimental projects. This includes training students in molecular biology techniques, cell-based assays, biochemical analyses, and research methodology, while mentoring them in scientific writing, data interpretation, and experimental planning. Through these activities, I aim to foster hands-on research skills and critical scientific thinking among emerging researchers in biotechnology and life sciences.