eSupervisor Detail

About me

PhD in Toxicology with 3.5 years of US Postdoc experience at UTHSC and USD. Expert in mitochondrial isolation, transplantation, and bioenergetics. Proficient in complex surgeries like CLP (sepsis model) and organ-specific procedures. Skilled in in-vivo/in-vitro models, GFR analysis (Medibeacon), and molecular techniques like Western blotting, RT-PCR, and ELISA. Focused on mitochondrial dysfunction, oxidative stress, and inflammation in AKI.

Interests: Research Interests 1. Mitochondrial Dynamics in Organ Injury My primary interest lies in understanding the pivotal role of mitochondrial dysfunction as a driver of Acute Kidney Injury (AKI). I am particularly interested in exploring mitochondrial bioenergetics, oxidative stress pathways, and the potential of mitochondrial transplantation as a regenerative therapeutic strategy to restore organ function. 2. Pathophysiology of Sepsis and Inflammation I am deeply invested in studying systemic inflammatory responses, specifically using the Cecal Ligation and Puncture (CLP) model. My focus is on investigating downstream therapeutic interventions that can mitigate the inflammatory cascade and improve survival outcomes in critical care settings. 3. Cardio-Renal Crosstalk and Systemic Failure I am also interested in the complex interplay between the heart and kidneys during injury states. My research aims to identify molecular biomarkers and signaling pathways that mediate organ-to-organ communication, focusing on how primary renal stress can lead to secondary cardiovascular complications.