Postdoctoral Research Fellow (Pdf)
Dr. Mahantheshkumar G T
Scientific Writing
About me
Ph.D. in Biotechnology with expertise in green nanobiotechnology, metal oxide nanoparticle synthesis, and translational cancer therapeutics. Experienced in phytochemical profiling, in vitro and in vivo pharmacological evaluation, and molecular biology techniques. Skilled in experimental design, data analysis, and scientific writing, with a strong focus on nanoparticle-mediated drug delivery and anticancer research.
Interests: Dr. Mahanthesh Kumar G T’s research interests are centered on translational nanobiotechnology and evidence-based phytopharmacology, with a strong focus on cancer therapeutics and metabolic disorders. His key research domains include: Green Nanobiotechnology – Eco-friendly synthesis of metal and metal oxide nanoparticles using medicinal plant extracts, with emphasis on scalable, reproducible, and sustainable nanofabrication strategies. Nanomedicine for Cancer Therapeutics – Design and development of nanoparticle-based drug delivery systems targeting breast cancer (including triple-negative breast cancer) and lung cancer, integrating physicochemical characterization with biological validation. Phytochemical Profiling and Bioactive Compound Isolation – Extraction, purification, and structural elucidation of plant-derived secondary metabolites (e.g., terpenoids such as trans-β-ionone) and evaluation of their pharmacological activities. Molecular Mechanisms of Anticancer Action – Investigation of apoptosis induction, oxidative stress modulation, mitochondrial dysfunction, and cell cycle arrest pathways using in vitro and in vivo experimental models. Antidiabetic and Enzyme Inhibition Studies – Evaluation of α-amylase and related metabolic enzyme inhibition using plant extracts and nanoparticle formulations as potential therapeutic agents. Antimicrobial and Antioxidant Studies – Assessment of biofunctionalized nanoparticles and phytocompounds against pathogenic microorganisms and oxidative stress models. Photocatalytic and Environmental Applications of Nanomaterials – Exploration of metal oxide nanoparticles for pollutant degradation and sustainable environmental remediation. Translational Research and Drug Development – Bridging natural product research, nanotechnology, and pharmacology to develop safe, cost-effective, and clinically relevant therapeutic candidates.
