eSupervisor Detail

About me

Molecular Biologist specializing in cell signalling and cardiovascular stress physiology. Over 8 years of expertise deciphering redox-dependent post-translational modifications (S-nitrosylation) and signaling pathways (PANoptosis, fibrosis) in cardiac disease. Proficient in small animal surgery, targeted nanotherapeutics, and cell culture. Published in high-impact journals with a proven track record of securing competitive national grants (DST-INSPIRE, ICMR).

Interests: As a molecular biologist specializing in cell signalling and stress physiology, my research investigates how oxidative and nitrosative stress dictate cellular fate, metabolic shifts, and tissue remodeling in cardiovascular and cardiometabolic diseases. Over the course of my doctoral and postdoctoral training, I have combined in vitro primary cultures, in vivo surgical and exercise preclinical models, and targeted nanotherapeutics to decode how redox-dependent post-translational modifications—such as protein S-nitrosylation of NEMO and FasR and molecular cross-talk drive inflammation, fibrosis, and cell death during myocardial infarction. My current work extends into the molecular dynamics of nitroxidative stress during regimented exercise and detraining-induced cardiac pathophysiology and therapeutic interventions for pathological cardiac hypertrophy. Moving forward, my research vision is to map how redox imbalances interact with immune signaling to govern vascular inflammation and tissue repair, with the ultimate long-term goal of establishing an independent research program dedicated to discovering targetable immunovascular signaling networks for cardiovascular therapeutics.